apbioinc

INTEGRATED TECHNOLOGY PLATFORM
FOR FUNCTIONAL ANTIBODY DISCOVERY

Human Antibody Phage Display Library

For Therapeutic Antibodies

SUPERB STABILITY, DIVERSITY & AFFINITY

  • Engineered phagemid allowing expression of rare antibody-phages
  • Covers 51 Vh and 40 Vk/31 VIgermline frameworks
  • 1.52 x 1011 diversity
  • sub nM affinity
  • Fab format

VALIDATED FOR DRUGGABLE TARGETS OF VARIOUS STRUCTURES

  • Tumor-associated carbohydrate antigen
  • Growth factor and receptor
  • Check-point protein
  • Ion channel
  • GPCR

BROAD ANTIGEN REACTIVITY

  • Whole cell
  • Protein
  • Peptide
  • Hapten

EXCELLENT EPITOPE COVERAGE

  • Self-antigens
  • Surface loops on multi-transmembrane proteins
  • Ligand-receptor interaction domains

Example of high-affinity, functional checkpoint antibodies
isolated from Omni-Mab Library